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Ulcerative Colitis Clinical Trial

Sponsored by Pfizer

Pfizer
NCT02958865 - Phase 2 - Interventional

Do you suffer from moderate to severe Ulcerative Colitis?

You may be eligible to participate in a clinical study for ulcerative colitis treatment.

Do you suffer from moderate to severe Ulcerative Colitis?

You may be eligible to participate in a clinical study for ulcerative colitis treatment.

Recruiting

Male & Female

18 - 70

years old

The purpose of this study is to determine whether PF-06651600 and PF-06700841 are effective in treatment of moderate to severe ulcerative colitis.

Why should I participate?

Ulcerative colitis (UC) is a chronic disease that can seriously affect quality of life for those who suffer from this painful condition. Defined by inflammation and ulceration of the colon, many people with UC experience symptoms of rectal bleeding, lower abdominal pain and diarrhea. Symptoms of UC may disappear during periods of remission that can last days, weeks or even years. The goal of medication is to keep people in remission longer.

A clinical research study is underway to evaluate the safety and effectiveness of two oral investigational medications for UC. The study is planning to enroll 360 adults in the US, Canada, Europe, Asia and the Middle East, aged 18 to 70 years of age, who have moderate to severe UC with inadequate response of symptoms from at least one standard UC treatment.

What's involved?

Participants in the study will be asked to attend 11 study clinic visits over a 10-month period including: a screening visit, a baseline visit, 8 study dosing and evaluation visits and a follow-up visit. Participants will receive investigational medication or placebo (a tablet that looks like the investigation medication but has no active ingredients) in a tablet form, to be taken once a day for 32 weeks.

At the start of the study, participants will be randomly assigned to one of the two study drug groups. Participants within each study group will then be randomly assigned to receive either active study drug or a placebo.

Study-related examinations and health assessments will be performed at each study visit and participants will be asked to complete study daily bowel movement diaries.

All study medication or placebo and study-related examinations and procedures are provided at no cost. Qualified participants may be reimbursed for time and travel.

Who can participate?

To be eligible to participate in this study you must meet several criteria including the following: you are between 18 and 70 years of age, you have been diagnosed with ulcerative colitis, you are willing to complete participant assessments and attend scheduled clinical visits, and you satisfy all of the eligibility requirements.

You will receive

Compensation of 90 per visit (11-15) + 50 travel

Where you'll go

Available locations

Long Beach Clinical Trials Services Inc

2008 Pacific Avenue, Long Beach, CA, USA 90806

Montefiore Medical Center

Bronx, NY, USA 10467

Abawi spol s r o

Bratislava, SVK 82107

View all 171 locations
Long Beach Clinical Trials Services Inc

2008 Pacific Avenue, Long Beach, CA, USA 90806

Montefiore Medical Center

Bronx, NY, USA 10467

Abawi spol s r o

Bratislava, SVK 82107

Advance Medical Research Center

Miami, FL, USA 33135

Amager og Hvidovre Hospital

30 Kettegård Alle, Hvidovre, DNK 2650

Amphia Ziekenhuis

Breda, NLD 4818 CK

Asklepios Westklinikum Hamburg

Hamburg, DEU 22559

ASST Rhodense Ospedale di Circolo di Rho

Rho, Milano (MI), ITA 20017

Baylor College of Medicine Baylor Medical Center

1 Baylor Plaza, Houston, TX, USA 77030

Borsod Abauj Zemplen Megyei Kozponti Korhaz

72-76 Szentpéteri kapu, Miskolc, HUN 3526

Brighton Surgical Center

9675 Brighton Way, Beverly Hills, CA, USA 90210

Bristol Hospital

85 Beleden Gardens Drive, Bristol, CT, USA 06010

Cascades Endoscopy Center

7120 Minstrel Way, Columbia, MD, USA 21045

Center for Digestive Health

4600 Investment Drive, Troy, MI, USA 48098

Central Connecticut Endoscopy Center

440 New Britain Avenue, Plainville, CT, USA 06062

Centrum Innowacyjnych Terapii Sp z o o

5/7 Ludwika Czajewicza, Piaseczno, POL 05-500

Centrum Medyczne Sw Lukasza Sp z o o

Czestochowa, POL 42-202

Centrum Zdrowia MDM

Warszawa, POL 00-635

Chevy Chase Endoscopy Center

5530 Wisconsin Avenue, Chevy Chase, MD, USA 20815

Clalit Health Services

Bat-Yam, ISR 5962025

Clements University Hospital

6201 Harry Hines Boulevard, Dallas, TX, USA 75390

Clinical Application Laboratories INC

4033 Third Avenue, San Diego, CA, USA 92103

Clinical Centre of Kragujevac

Kragujevac, SRB 34000

Clinical Hospital Center Zemun

Zemun, Belgrade, SRB 11080

Concorde Medical Group PLLC

30 East 40th Street, New York, NY, USA 10016

Connecticut Clinical Research Foundation

39 Brewster Road, Bristol, CT, USA 06010

Del Sol Research Managment LLC

850 North Kolb Road, Tucson, AZ, USA 85710

Desert Sky Gastroenterology PLLC

Tucson, AZ, USA 85712

Diabetes and Endocrinology Unit

Tel Aviv, ISR 6203854

Endomed s r o

Vranov nad Toplou, SVK 093 01

Endoskopia SP Z O O

Sopot, POL 81-756

ETG Kielce

Kielce, POL 25-364

EUGASTRO GmbH

Leipzig, DEU 04103

Feldman ENT

5454 Wisconsin Avenue, Chevy Chase, MD, USA 20815

Gastro Center Of Maryland

7120 Minstrel Way, Columbia, MD, USA 21045

Gastro One

1324 Wolf Park Drive, Germantown, TN, USA 38138

Gastrointestinal Biosciences

2080 Century Park East, Los Angeles, CA, USA 90067

GASTROMED Sp z o o

Lublin, POL 20-582

Gastrostudien GbR

Berlin, DEU 10825

General Hospital Djordje Joanovic

Zrenjanin, SRB 23000

General Hospital Subotica

Subotica, SRB 24000

Great Lakes Gastroenterology Research LLC

8877 Mentor Avenue, Mentor, OH, USA 44060

Gulf Coast Research Group

Houston, TX, USA 77098

H T Centrum Medyczne

Tychy, POL 43-100

Hepato Gastroenterologie HK s r o

Hradec Kralove, 50012

Hospital Clinic de Barcelona

Barcelona, ESP 08036

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona, ESP 08907

Hospital Universitario Donostia

San Sebastian, Guipuzkoa, ESP 20014

Hospital Universitario Fundacion Alcorcon

Alcorcon, Madrid, ESP 28922

Hospital Universitario Marques de Valdecilla

25 Avenida Valdecilla, Santander, Cantabria, ESP 39008

Illinois Gastroenterology Group

1415 South Arlington Heights Road, Arlington Heights, IL, USA 60005

Istituto Clinico Humanitas

Rozzano, Milan (MI), ITA 20089

Kips Bay Endoscopy Center

535 2nd Avenue, New York, NY, USA 10016

KM Management spol s r o

Nitra, SVK 949 01

Krankenhaus Waldfriede e V

Berlin, DEU 14163

Lexmedica

Wroclaw, POL 53-114

Lonestar Endoscopy LLP Endoscopy Location

180 Bear Creek Parkway, Keller, TX, USA 76248

McGuire DMVA

1201 Broad Rock Boulevard, Richmond, VA, USA 23249

Medak s r o

Bratislava, SVK 851 01

Medial Pharma s r o .,

Hradec Kralove, 50012

Medical Associates Research Group

8008 Frost Street, San Diego, CA, USA 92123

Melita Medical Sp z o o .

Wroclaw, POL 50-449

MGG Group Co Inc Chevy Chase Clinical Research

5550 Friendship Boulevard, Chevy Chase, MD, USA 20815

Migdal Hamea Clinic

Tel Aviv, ISR 6203854

New York University Langone Medical Center

333 East 38th Street, New York, NY, USA 10016

Nordsjaellands Hospital Frederikssund Endoscopy only )

30 Frederikssundsvej, Frederikssund, DNK 3600

North Shore University Hospital

300 Community Drive, Manhasset, NY, USA 11030

Northwell Health Division of Gastroenterology

865 Northern Boulevard, Great Neck, NY, USA 11021

NYU Clinical Cancer Center

160 East 34th Street, New York, NY, USA 10016

NYU Langone Long Island Clinical Research Associates

1000 Northern Boulevard, Great Neck, NY, USA 11021

NYU Langone Medical Center

333 East 38th Street, New York, NY, USA 10016

NYU Langone Nassau Gastroenterology Associates

1000 Northern Boulevard, Great Neck, NY, USA 11021

NYU Medical Science Building

540 1st Avenue, New York, NY, USA 10016

Paian MED Research GmbH

Berlin, DEU 10318

Pannonia Maganorvosi Centrum

35 Pannónia utca, Budapest, HUN 1136

Parkland Health and Hospital System

Dallas, TX, USA 75235

Pharmacy Services

Holon, ISR 5810001

Pharmacy Services

Bat-Yam, ISR 5962025

San Diego Endoscopy Center

4033 Third Avenue, San Diego, CA, USA 92103

Semmelweis Egyetem II Belgyogyaszati Klinika

46 Szentkirályi utca, Budapest, HUN 1088

Surgical Centers of Michigan

4600 Investment Drive, Troy, MI, USA 48098

Szent Margit Korhaz Gasztroenterologiai Osztaly

132 Bécsi út, Budapest, HUN 1032

Texas Diegestive Consultants Adminitrative Regulatory

505 Nolen Drive, Southlake, TX, USA 76092

The E Wolfson Medical Center

Holon, ISR 5810001

The Endoscopy Center of Lake County

9614 Old Johnnycake Ridge Road, Mentor, OH, USA 44060

The Feinstein Institute for Medical Research

350 Community Drive, Manhasset, NY, USA 11030

Tolna Megyei Balassa Janos Korhaz

Szekszard, HUN 7100

UMASS Memorial Medical Center

55 North Lake Avenue, Worcester, MA, USA 01655

Universitaetsklinikum Bonn

Bonn, DEU 53127

Universitaetsklinikum Ulm

Ulm, DEU 89081

University of Massachusetts Medical School

55 North Lake Avenue, Worcester, MA, USA 01655

University of Miami Hospital

1400 Northwest 12th Avenue, Miami, FL, USA 33136

University of Miami Hospital and Clinics

1400 Northwest 12th Avenue, Miami, FL, USA 33136

University of Rochester Medical Center

601 Elmwood Avenue, Rochester, NY, USA 14642

University of Washington

Seattle, WA, USA 98195

Ustavni lekarna

Strakonice, 38601

UT Southwestern Medical Center

5323 Harry Hines Boulevard, Dallas, TX, USA 75390

UT Southwestern Medical Center CRU Aston

5303 Harry Hines Boulevard, Dallas, TX, USA 75390

Vanderbilt University Medical Center

Nashville, TN, USA 37232-5543

Vanderbilt University Medical Center

Nashville, TN, USA 37212-1610

Vanderbilt University Medical Center

Nashville, TN, USA 37232-7610

Vanderbilt University Medical Center

1211 Medical Center Drive, Nashville, TN, USA 37232

Vanderbilt University Medical Center IBD Clinic

Nashville, TN, USA 37212-1375

Verity Research

Fairfax, VA, USA 22031

Weill Cornell Medical College

New York, NY, USA 10021

Interested in participating?
Sponsored by
Pfizer

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