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Alzheimer's Disease Clinical Trial

Sponsored by Biogen

NCT02484547 - Phase 3 - Interventional

Having memory problems or trouble thinking clearly?

If this sounds like you, or someone you know, please consider the EMERGE Study.

Having memory problems or trouble thinking clearly?

If this sounds like you, or someone you know, please consider the EMERGE Study.


Male & Female

50 - 85

years old

The primary objective of the study is to evaluate the efficacy of monthly doses of aducanumab in slowing cognitive and functional impairment as measured by changes in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) score as compared with placebo in participants with early AD. Secondary objectives are to assess the effect of monthly doses of aducanumab as compared with placebo on clinical progression as measured by Mini-Mental State Examination (MMSE), AD Assessment Scale-Cognitive Subscale (13 items) [ADAS-Cog 13], and AD Cooperative Study-Activities of Daily Living Inventory (Mild Cognitive Impairment version) [ADCS-ADL-MCI].

Why should I participate?

The EMERGE Study is a global study assessing the efficacy and safety of an investigational medication, to determine whether it can slow the progression of symptoms in early Alzheimer’s disease.

There is an important medical and scientific need to research therapies that could delay memory loss and the progression of disability in Alzheimer’s disease because there are currently no approved treatments that slow the course of the condition.

What's involved?

You will need a study partner – someone who is close to you, such as a family member or close friend – to attend certain study visits with you and provide information on your health and well-being.If eligible, all study medication, examinations, and medical care related to the study will be provided at no cost to you. Reasonable compensation for time and travel may be provided.

Who can participate?

You may be able to take part in the EMERGE Study if you are 50 –85 years of age and are experiencing symptoms that might be related to early Alzheimer’s disease, such as problems with memory or thinking clearly.

You will receive

Compensation of $100 per visit for xx visits

Where you'll go

Available locations

Clinical Trial Network

7080 Southwest Freeway, Houston, TX, USA 77074

Meridien Research

Brooksville, FL, USA 34601

ActivMed Practices Research

Portsmouth, NH, USA 03801

View all 169 locations
Clinical Trial Network

7080 Southwest Freeway, Houston, TX, USA 77074

Meridien Research

Brooksville, FL, USA 34601

ActivMed Practices Research

Portsmouth, NH, USA 03801

AdvanceMed Research

Lawrenceville, NJ, USA 08648

Akademiska sjukhuset

Uppsala, SWE 75185

ALTHAIA Hospital Sant Joan de Deu

Manresa, Barcelona, ESP 08243

Alzheimer Research Center

Amsterdam, NLD 1081 GM

Amphia Ziekenhuis

Breda, NLD 4818 CK

Anderson Clinical Research

Redlands, CA, USA 92354

Associated Neurologists of Southern Connecticut PC

75 Kings Highway Cutoff, Fairfield, CT, USA 06824

ASST di Monza

Monza, Milano, ITA 20052

Axiom Clinical Research of Florida

2919 West Swann Avenue, Tampa, FL, USA 33609

AZ Delta

Roeselare, BEL 8800

AZ Groeninge Campus Kennedylaan

Kortrijk, BEL 8500

AZ Klina

Brasschaat, BEL

AZ Sint Jan Brugge

Brugge, BEL 8000

Azienda Ospedaliera Card G Panico

Tricase, Lecce, ITA 73039

Banner Alzheimer's Institute

901 East Willetta Street, Phoenix, AZ, USA 85006

Banner Sun Health Research Institute

10515 West Santa Fe Drive, Sun City, AZ, USA 85351

Bezirkskrankenhaus Guenzburg

Guenzburg, Baden Wuerttemberg, DEU 89312

Boston Center for Memory

Newton, MA, USA 05201

Bradenton Research Center Inc

3924 9th Avenue West, Bradenton, FL, USA 34205

Bruyere Continuing Care

43 Bruyère Street, Ottawa, Ontario, CAN K1N 5C8

California Pacific Medical Center

Castro Street, San Francisco, CA, USA 94114

Centrum Medyczne Medyk

Rzeszow, POL 35-055

CHU de Toulouse Hôpital Purpan

Toulouse cedex 9, Haute Garonne, FRA 31059

CHU Nantes Hopital Nord Laënnec

Nantes cedex 1, Loire Atlantique, FRA 44093

CHU Rennes Hopital Pontchaillou

Rennes cedex 09, Ille Et Vilaine, FRA 35033

Cleveland Clinic Lou Ruvo Center for Brain Health

888 West Bonneville Avenue, Las Vegas, NV, USA 89106

Clinica Universidad de Navarra

36 Avenida de Pío XII, Pamplona, Navarra, ESP 31008

Clinical Neuroscience Solutions Inc

618 East South Street, Orlando, FL, USA 32801

Complejo Hospitalario de Caceres

Caceres, Cáceres, ESP 10003

DIEX Recherche Sherbrooke Inc

Sherbrooke, Quebec, CAN J1H 1Z1

Douglas Hospital Research Centre

Verdun, Quebec, CAN H4H 1R3

emovis GmbH

Berlin, DEU 10629

Empire Neurology PC

1182 Troy Schenectady Road, Latham, NY, USA 12110

Erasmus Medisch Centrum

Rotterdam, NLD 3015 CE

Excell Research Inc

3998 Vista Way, Oceanside, CA, USA 92056

Florida Atlantic University

777 Glades Rd, Boca Raton, FL, USA 33431

Hattiesburg Clinic P A

415 South 28th Avenue, Hattiesburg, MS, USA 39401

Health Research

Kamloops, British Columbia, CAN

Health Research

West Vancouver, British Columbia, CAN

Hoag Memorial Hospital Presbyterian

1 Hoag Drive, Newport Beach, CA, USA 92663

Hôpital de la Timone

Marseille, Bouches-du-Rhône, FRA 13385

Hôpital des Charpennes

Villeurbanne, Rhone, FRA 69100

Hôpital Fernand Widal

Paris, FRA 75010

Hôpital Gui de Chauliac

Montpellier, Herault, FRA 34295

Hopital Roger Salengro CHU Lille

Lille Cedex, Nord, FRA 59037

Hospital de Basurto

Bilbao, Vizcaya, ESP 48013

Hospital Del Mar

Barcelona, ESP 08003

Hospital General Universitario de Elche

Elche, Alicante, ESP 3203

Hospital Universitario Reina Sofía

Cordoba, Córdoba, ESP 14011

IMMUNOe International Research Centers

3260 East 104th Avenue, Thornton, CO, USA 80233

Infinity Clinical Research LLC

Hollywood, FL, USA 33021

Institute for Memory Impairments

Irvine, CA, USA 92607

ISPG Institut fuer Studien zur Psychischen Gesundheit

Mannheim, Baden Wuerttemberg, DEU 68165

Jbn Medical Diagnostic Services Inc

301-2951 Walkers Line, Burlington, Ontario, CAN L7M 4Y1

JEM Research Institute

Atlantis, FL, USA 33462

Jewish General Hospital NETWORK

Montreal, Quebec, CAN H3T 1E2

Josephson Wallack Munshower Neurology P C

7250 Clearvista Drive, Indianapolis, IN, USA 46256

Kawartha Regional Memory Clinic

168 Brock Street, Peterborough, Ontario, CAN K9H 2P4

Kennemer Gasthuis Zuid

Haarlem, NLD 2035 RC

Klinik Hohe Warte Bayreuth

8 Hohe Warte, Bayreuth, Bayern, DEU 95445

Klinikum Altenburger Land GmbH

Altenburg, Thueringen, DEU 04600

Klinikum Chemnitz gGmbH

Chemnitz, Sachsen, DEU 09131

Klinikum rechts der Isar der TU Muenchen

Muenchen, Bayern, DEU 81675

Kopfzentrum Leipzig

9 Fichtestraße, Leipzig, Sachsen, DEU 04275

Lehigh Center for Clinical Research LLC

401 North 17th Street, Allentown, PA, USA 18104

Mayo Clinic in Florida

4500 San Pablo Road South, Jacksonville, FL, USA 32224

Mclean Hospital

115 Mill Street, Belmont, MA, USA 02478

Medical Research Health and Education Foundation Inc

7196 North Lake Drive, Columbus, GA, USA 31909

Medizinisches Zentrum MZB Biel

Biel/Bienne, CHE 2502

mMED Maciej Czarnecki

Warszawa, POL 01-697

Mount Sinai School Of Medicine

1 Gustave L. Levy Place, New York, NY, USA 10029

Nervenfachaerztlichen Gemeinschaftspraxis Ulm

Ulm, Baden Wuerttemberg, DEU 89078

Neuro Centrum Odenwald

8 Albert-Schweitzer-Straße, Erbach, Hessen, DEU 64711

Neuropraxis Muenchen Sued

2 Hauptstraße, Unterhaching, Bayern, DEU 82008

Neurostudies net LLC

2665 North Decatur Road, Decatur, GA, USA 30033

Northwest Neurological PLLC

610 South Sherman Street, Spokane, WA, USA 99202

Ohio State University Medical Center

Dublin, OH, USA 43017

Ospedale Civico

Lugano, CHE 6903

Ospedale degli Infermi

Ponderano, Biella, ITA 13875

Pacific Neuroscience Medical Group

1701 Solar Drive, Oxnard, CA, USA 93030

Pacific Research Network

3003 Fourth Avenue, San Diego, CA, USA 92103

PALLMED Sp z o o

Bydgoszcz, POL 85-796

Penn Memory Center

Philadelphia, PA, USA 19104

PMG Research of Winston Salem LLC

1901 South Hawthorne Road, Winston-Salem, NC, USA 27103

Podlaskie Centrum Psychogeriatrii

Bialystok, POL 15-732

Praxis Dr Kluenemann

40A Hauptstraße, Wenzenbach, Bayern, DEU 93173

Quantum Laboratories Inc

Deerfield Beach, FL, USA 33064

Recherche Sepmus Inc

Greenfield Park, Quebec, CAN J4V 2J2

Recherches Neuro Hippocampe Inc

Gatineau, Quebec, CAN J8T 8J1

Renewal Behavioral Health

Long Beach, CA, USA 85013

Research Center for Clinical Studies Inc

71 East Avenue, Norwalk, CT, USA 06851

Research Site

Shizuoka-shi, Shizuoka-Ken, JPN 420-8688

Research Site

Kyoto-shi, Kyoto-Fu, JPN 607-8113

Research Site

Kishiwada-shi, Osaka-Fu, JPN 596-8522

Research Site

Kurume-shi, Fukuoka-Ken, JPN 830-0011

Rhode Island Hospital

593 Eddy Street, Providence, RI, USA 02903

Roper St Francis Healthcare

North Charleston, SC, USA 29406-6076

Senior Adult Specialty Research

3215 Steck Avenue, Austin, TX, USA 78757

St Joseph Heritage Healthcare

Santa Rosa, CA, USA 95403

St Joseph's HC Parkwood Institute

London, Ontario, CAN N6C 5J1

Stanford University Medical Center

300 Pasteur Drive, Stanford, CA, USA 94305

Syrentis Clinical Research

1401 North Tustin Avenue, Santa Ana, CA, USA 92705

Terveystalo Kamppi

Helsinki, FIN 00100

The Methodist Hospital Research Institute

6670 Bertner Avenue, Houston, TX, USA 77030

Toronto Western Hospital

399 Bathurst Street, Toronto, Ontario, CAN M5T 2S8

True North Clinical Research Halifax Inc

Halifax, Nova Scotia, CAN B3S 1M7

True North Clinical Research Kentville Inc

70 Exhibition Street, Kentville, Nova Scotia, CAN B4N 4K9

Universitaetsklinikum Duesseldorf AoeR

Duesseldorf, Nordrhein Westfalen, DEU 40629

Universitaetsklinikum Muenster

Muenster, Nordrhein Westfalen, DEU 48149

Universitaetsklinikum Ulm

Ulm, Baden Wuerttemberg, DEU 89081

Universitair Ziekenhuis Brussel

Bruxelles, BEL 1090

University of Alabama at Birmingham

Birmingham, AL, USA 35233

University of California San Diego Medical Center

200 West Arbor Drive, San Diego, CA, USA 92103

University of Colorado Denver

13001 East 17th Place, Aurora, CO, USA 80045

University of Utah Health Sciences Center

50 North Medical Drive, Salt Lake City, UT, USA 84132

University of Washington Medical Center

1959 Northeast Pacific Street, Seattle, WA, USA 98195

USC Keck School of Medicine

1975 Zonal Avenue, Los Angeles, CA, USA 90033

UZ Leuven

Leuven, BEL 3000

Wake Forest Baptist Health

Winston-Salem, NC, USA 27103

Weill Cornell Medical College New York Presbyterian Hospital

520 East 70th Street, New York, NY, USA 10021

Xenoscience Inc

500 West Thomas Road, Phoenix, AZ, USA 85013

Yale University School of Medicine

333 Cedar Street, New Haven, CT, USA 06520

Interested in participating?
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