Have you or your loved ones been diagnosed with advanced solid tumors?

You may be eligible to participate in a advanced solid tumors clinical trial.

Have you or your loved ones been diagnosed with advanced solid tumors? You may be eligible to participate in a advanced solid tumors clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Advanced Solid Tumors Clinical Trial in Bethesda MD
NCT01625234 | Phase 1 phase 2 | Interventional

Have you or your loved ones been diagnosed with advanced solid tumors?

You may be eligible to participate in a advanced solid tumors clinical trial.

Have you or your loved ones been diagnosed with advanced solid tumors? You may be eligible to participate in a advanced solid tumors clinical trial.

Completed

Male & Female

18 Years +

This study has recruited 131 Participants

This is the first human study to use X-396 (ensartinib), a drug being developed for treatment of advanced cancers. The initial purpose of the study is to determine the largest amount of X-396 that can be safely given to humans (the maximum tolerated dose). Once the recommended Phase 2 dose has been determined, an expansion phase will assess the preliminary anti-tumor activity of X-396 in ALK-positive non-small cell lung cancer. The study will also provide early information on how the body handles the drug (pharmacokinetics) and on the efficacy of X-396.