Are you healthy and looking to help advance medical science?

You may be eligible to participate in a atrial fibrillation clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a atrial fibrillation clinical study, and could be compensated for your time.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Atrial Fibrillation Clinical Trial in Calgary Alberta
NCT01608893 | Interventional

Are you healthy and looking to help advance medical science?

You may be eligible to participate in a atrial fibrillation clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a atrial fibrillation clinical study, and could be compensated for your time.

Active not recruiting

Male & Female

18 - 90

Years old

This study is looking to recruit 300 Participants

Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated with significant symptoms and health problems including an increased risk of stroke and death. Current drug therapies are often ineffective and associated with significant side effects. Abnormalities of calcium regulation in cells may lead to triggers for AF. Emerging data suggest that abnormal intracellular calcium regulation mediated through the ryanodine receptor in heart cells may contribute to AF. Recently the investigators have shown that the β-blocker carvedilol which is most commonly used to treat patients with heart failure, modifies calcium regulation mediated through the ryanodine receptor. At present this drug is not frequently used to treat AF. Therefore the investigators will conduct a randomized trial comparing carvedilol to metoprolol for prevention of paroxysmal AF. This may result in improved health and quality of life for people who suffer AF.