Have you or your loved ones been diagnosed with glioma?

You may be eligible to participate in a glioma clinical trial.

Have you or your loved ones been diagnosed with glioma? You may be eligible to participate in a glioma clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

H3 K27M-mutant High-Grade Glioma in Houston TX
NCT03295396 | Phase 2 | Interventional
Chimerix
Sponsored by
Chimerix

Have you or your loved ones been diagnosed with glioma?

You may be eligible to participate in a glioma clinical trial.

Have you or your loved ones been diagnosed with glioma? You may be eligible to participate in a glioma clinical trial.

Active not recruiting

Male & Female

18 Years +

This study is looking to recruit 95 Participants

The primary objective of this phase II trial is to determine the efficacy and safety of ONC201, an oral small molecule imipridone DRD2 antagonist, in adult subjects with recurrent high-grade glioma. This study will test the research hypothesis that histone H3 K27M mutation sensitizes to oral administration of ONC201 in gliomas.