Have you or your loved ones been diagnosed with asthma in children?

You may be eligible to participate in a asthma in children clinical trial.

Have you or your loved ones been diagnosed with asthma in children? You may be eligible to participate in a asthma in children clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Asthma in Children Clinical Trial in Paris
NCT03229317 | Observational

Have you or your loved ones been diagnosed with asthma in children?

You may be eligible to participate in a asthma in children clinical trial.

Have you or your loved ones been diagnosed with asthma in children? You may be eligible to participate in a asthma in children clinical trial.

Completed

Male & Female

5 - 6

Years old

This study has recruited 142 Participants

Early lung function deficits represent a significant risk factor for the evolution toward chronic obstructive pulmonary disease later in life. Prematurity and in utero tobacco smoke exposure are already known to predispose children to develop a non-reversible obstructive ventilatory defect in adulthood. The role of vitamin D status during pregnancy is less certain. In humans, low vitamin D concentrations during pregnancy are associated to an increased risk of asthma in children. In murine models, low vitamin D concentrations during pregnancy are associated to structural abnormalities of the airways in mouse pups. Investigators hypothesized that vitamin D play a role in early airways development, from the first trimester of pregnancy. To bring arguments to this hypothesis, the investigators will study the association of airway resistance in children aged 5 to 6 years old with the concentration of vitamin D during the first trimester of pregnancy in their mothers.