Are you healthy and looking to help advance medical science?

You may be eligible to participate in a adrenal cancer clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a adrenal cancer clinical study, and could be compensated for your time.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Adrenal Cancer Clinical Trial in Haifa
NCT03083834 | Interventional

Are you healthy and looking to help advance medical science?

You may be eligible to participate in a adrenal cancer clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a adrenal cancer clinical study, and could be compensated for your time.

Recruiting

Male & Female

18 - 80

Years old

This study is looking to recruit 50 Participants

In mitotane treated patients, serum cortisol cannot be used to diagnose hypoadrenalism, since mitotane increases cortisol binding globulin levels (CBG), artificially raising total cortisol. Salivary free cortisol (SC) is not affected by CBG alterations, and reflects the free serum cortisol. In the current study, investigators will assess serum and SC responses during low-dose cosyntropin stimulation test in healthy volunteers, mitotane-induced hypoadrenal patients on steroid replacement therapy and in patients who suffer from hypoadrenlism caused from other etiology. Investigators will compare results between groups and try to demonstrate the superiority of SC in assessing adrenal function in mitotane treated patients.