Have you or your loved ones been diagnosed with breast cancer?

You may be eligible to participate in a breast cancer clinical trial.

Have you or your loved ones been diagnosed with breast cancer? You may be eligible to participate in a breast cancer clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Breast Cancer Clinical Trial in Shanghai Shanghai
NCT01352091 | Phase 3 | Interventional
Fudan University
Sponsored by
Fudan University

Have you or your loved ones been diagnosed with breast cancer?

You may be eligible to participate in a breast cancer clinical trial.

Have you or your loved ones been diagnosed with breast cancer? You may be eligible to participate in a breast cancer clinical trial.

Unknown status

Female

18 Years +

This study is looking to recruit 670 Participants

The present study is a randomized open-label -phase III study that aims to compare the efficacy of Zoladex® combined with Aromidex® for 3-2 years after SERMs (tamoxifen and Fareston®) as an adjuvant therapy for 2-3 years with the efficacy of tamoxifen up to 5 years for premenopausal breast cancer women with hormone receptor positive, lymph node positive or tumor ≥4cm. According to St. Gallen's guideline, hormone receptor positive was defined as endocrine responsive and endocrine response uncertain categories (table 3-1), and only those with ER or PR expression undetectable were considered as HR negative. The pathological evaluation of axillary lymph node could be done by sentinel node biopsy (SNB) when axillary nodes were clinically impalpable accompanied with axillary lymph node dissection (ALND) or directly through ALND when axillary nodes appeared to be positive in clinical examination. Based on the operating standard of local medical institution, identifying the numbers of lymph nodes to do the pathological evaluation and to do the dissection of I- or II-station nodes accurately.