Are you healthy and looking to help advance medical science?

You may be eligible to participate in a alzheimer's disease clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a alzheimer's disease clinical study, and could be compensated for your time.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Alzheimer's Disease Clinical Trial in Angers

NCT01315704 | Observational

Are you healthy and looking to help advance medical science?

You may be eligible to participate in a alzheimer's disease clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a alzheimer's disease clinical study, and could be compensated for your time.

Unknown status

Male & Female

All ages

This study is looking to recruit 700 Participants

The purpose of this study is to compare characteristics of gait and balance measured among patients with Alzheimer's disease or related disorders separated into 3 groups according to the stage of disease (i.e., pre-dementia, mild and moderate dementia stages); to determine the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities; and to establish a database at Angers University Memory Centre.

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Details for the study

Population

All patients of the University Memory Center of Angers University Hospital with respect to the eligibility criteria

Brief Title

Alzheimer's Disease and Related Disorders

Official Title

Maladie d'Alzheimer et Maladies apparentées : Caractérisation Des Anomalies Cognitivo-motrices, et Des Effets Des médicaments Anti-démence et de la Vitamine D à Partir de la Mise en Place d'Une Base de données au CMRR du CHU d'Angers

Brief Summary

The purpose of this study is to compare characteristics of gait and balance measured among<br /> patients with Alzheimer's disease or related disorders separated into 3 groups according to<br /> the stage of disease (i.e., pre-dementia, mild and moderate dementia stages); to determine<br /> the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities; and to<br /> establish a database at Angers University Memory Centre.

Detailed Description

Although gait disorders are frequently associated with Alzheimer's disease and related
disorders (ADRD), few studies have focused on cognitive motor effects of anti-dementia drugs
and vitamin D.

The objectives of this study are to

- Compare characteristics of gait and balance measured among patients with ADRD separated
into 3 groups according to stages of disease (i.e., pre-dementia, mild and moderate
dementia stages)

- To determine the effects of anti-dementia drugs and vitamin D on cognitive motor
abnormalities

- To determine whether motor abnormalities could be associated with cognitive impairments,
specifically executive dysfunctions

- To establish a database at Angers University Memory Center.

Treatments and/or Procedures

Drug intervention

before-after interventional (anti-dementia drugs and/or vitamin D) study

Study Criteria

Inclusion Criteria:

  -  All elderly patients from the University Memory Center of Angers University Hospital.

  -  Able to walk without any walking aid on 15 meters

  -  Mini-Mental Status Examination score > 10

  -  Being affiliated to a social security regime

Exclusion Criteria:

  -  Mini-Mental Status Examination score ≤ 10

  -  Subject suffering from pre-existing impellent disturbances

  -  History of cerebrovascular accident or other cerebro-spinal pathology

  -  Poor workmanship of the written or oral French language

  -  Use of walking aid such as walking frame with wheels or tricycle.

  -  Acute medical or surgical disease in the past 3 months

  -  Refusal to participate (or trustworthy person)

  -  Near visual acuity < 2/10