RATIONALE: Collecting and storing samples of tissue, blood, and body fluid from patients with cancer to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing blood and tissue samples from patients being evaluated for hematologic cancer.

Population

Hematologic malignancies

Brief Title

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Official Title

Tissue Procurement For Hematolymphoid Conditions

Brief Summary

RATIONALE: Collecting and storing samples of tissue, blood, and body fluid from patients with <br /> cancer to study in the laboratory may help the study of cancer in the future. <br /> <br /> PURPOSE: This research study is collecting and storing blood and tissue samples from patients <br /> being evaluated for hematologic cancer.

Detailed Description

OBJECTIVES:

- Provide source of patient tissue, blood, and body fluid samples for ongoing diagnostic,
prognostic, or immune-monitoring studies.

- Support and enhance translational, clinical and basic research for Lineberger
Comprehensive Cancer Center (LCCC) members (and non-members who have an LCCC member as
sponsor and collaborator) with IRB-approved studies.

- Maintain responsible and appropriate policies and procedures that ensure good patient
care and responsible conduct of research.

- Address medical and legal issues, and protect participant and patient privacy and
confidentiality.

- Provide a responsible and uniform mechanism for the integrated coordination of the
hemato-pathologist and surgeon or hematology/oncology staff, researcher, and protocol
office to obtain appropriate specimens for researchers.

- Support young investigators to obtain pilot data for grant funding.

OUTLINE: Patients undergo tissue, blood, and body fluid collection during diagnostic or
routine procedures for future correlative studies. Tissue samples may include, but are not
limited to, lymph node or non-nodal biopsies, bone marrow biopsy and/or aspirate, blood and
serum, and buccal swabs for germline DNA analysis.