This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is different from adults. Cephalosporins and macrolide antibiotics are the common drugs for children with community acquired pneumonia, the investigators aim to study the population pharmacokinetics of cephalosporins and macrolide antibiotics in children receiving the drug for treatment of community acquired pneumonia, and to correlate it with treatment effectiveness and incidence of adverse effects. Potential Impact: This novel knowledge will allow better and more rational approaches to the treatment of community acquired pneumonia. It will also set the foundation for further studies that will be able to test improved therapies that may increase treatment response in vulnerable children.

Population

Children (1-18 years of age) receiving drugs per standard of care as prescribed by treating caregiver.

Brief Title

Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia

Official Title

Population Pharmacokinetics of Cephalosporins and Macrolides in Children With Community Acquired Pneumonia

Brief Summary

This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is<br /> different from adults. Cephalosporins and macrolide antibiotics are the common drugs for<br /> children with community acquired pneumonia, the investigators aim to study the population<br /> pharmacokinetics of cephalosporins and macrolide antibiotics in children receiving the drug<br /> for treatment of community acquired pneumonia, and to correlate it with treatment<br /> effectiveness and incidence of adverse effects.<br /><br /> Potential Impact: This novel knowledge will allow better and more rational approaches to the<br /> treatment of community acquired pneumonia. It will also set the foundation for further<br /> studies that will be able to test improved therapies that may increase treatment response in<br /> vulnerable children.