Have you experienced a mild traumatic brain injury and suffer from PTSD?

You may be eligible to participate in this study.

Have you experienced a mild traumatic brain injury and suffer from PTSD? You may be eligible to participate in this study.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Recruiting for this study? Get access to patient recruitment tools.
Mild Traumatic Brain Injury & PTSD Study
NCT03819608 | Interventional

What you may receive

Study related treatment at no cost

Free parking at Northwestern University for visits

Compensation of up to $575

Theresa Pape
Sponsored by
Theresa Pape

Have you experienced a mild traumatic brain injury and suffer from PTSD?

You may be eligible to participate in this study.

Have you experienced a mild traumatic brain injury and suffer from PTSD? You may be eligible to participate in this study.

Recruiting

Male & Female

18 - 60

Years old

This study is looking to recruit 200 Participants

This study is evaluating potential treatments to reduce attention problems and improve everyday function for patients with PTSD and mild traumatic brain injury. Over the course of 10 weeks, this study will use a combination of two treatments: 1. Interactive computer attention processing training. 2. A non-invasive treatment that uses magnets to change brain activity, also known as intermittent theta burst stimulation (iTBS). The trial will study the effectiveness of combining these treatments by assessing the patient’s persistent attention deficits. Please see the FAQ section for more additional information on these treatments.

Why should I participate?

Your participation will help the research team evaluate whether the treatment effectively reduces attention problems, allowing improved everyday function. The study treatments use a combination of iTBS and an attention training program to potentially yield better results than traditionally available treatments.

What's involved?

Your participation in the study will last approximately 10 weeks or 2 ½ months. During the first 4 weeks, you will have 2-3 visits per week (10-12 in total) during which you will receive assessments, an MRI and treatment including iTBS and attention training. Each visit will last ½ day to a full day. Approximately four weeks after the treatment is complete (week 8-10 overall), you will have one follow up visit.

Who can participate?

Patients ages 18-60, who have experienced a mild traumatic brain injury (or concussion) in the past ten years, and also suffer from PTSD, are eligible to participate in this study. However, if the patient experiences active seizures, is treated for seizures or is unable to have an MRI, they are not eligible to participate in this study.

Available locations
Northwestern University

Northwestern University

Recruiting Chicago, IL, USA 60141

Edward Hines Jr VA Hospital

Edward Hines Jr VA Hospital

Recruiting 5000 5th Avenue, Hines, IL, USA 60141

Frequently Asked Questions
What is iTBS?

iTBS is a type of transcranial magnetic stimulation. It is a non-invasive treatment that uses magnets on top of your head to change brain activity.

What will the attention training involve?

Attention training will be completed immediately after each iTBS session. A research assistant will set up a computer program where you will complete the training.

What tests are involved?

You will complete testing throughout your participation that includes filling out questionnaires about your symptoms and activities of daily living, tests of your thinking and memory skills, and will have an MRI completed three different times during your participation.

Can my doctor get the results of my tests?

Testing results will be reviewed with you at the end of your participation in the study and can be shared with your physician. MRI images are not available in a readable format to be given to you, but you would be notified if any concerning findings were noted.

How long are study sessions?

Sessions vary in length depending on what is being performed that day, but last approximately a half to full day. We will work to complete your schedule at the start of participation, so that you know when and for how long you would be needed each day.

Interested in learning more?
Theresa Pape
Sponsored by Theresa Pape

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