Are you healthy and looking to help advance medical science?

You may be eligible to participate in a acne clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a acne clinical study, and could be compensated for your time.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Acne Clinical Trial in Cleveland OH

NCT02457000 | Observational

Are you healthy and looking to help advance medical science?

You may be eligible to participate in a acne clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a acne clinical study, and could be compensated for your time.

Completed

Male & Female

18 Years +

This study has recruited 59 Participants

The purpose of this study is to explore the mechanisms behind how sleep quality may affect skin aging, skin integrity and skin disease.

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Details for the study

Population

Adults from Northeast Ohio who are either healthy, normal volunteers or have skin pathology including but not limited to eczema, psoriasis, acne, and other inflammatory dermatoses

Brief Title

Sleep, Circadian Rhythm & Skin Health

Official Title

Sleep, Circadian Rhythm & Skin Health

Brief Summary

The purpose of this study is to explore the mechanisms behind how sleep quality may affect <br /> skin aging, skin integrity and skin disease.

Outcome Measures

Outcome measures are the tests that investigators perform to prove whether or not a treatment being tested in a clinical trial is having any effect.

Primary

Analysis of Sleep Pattern via Actigraphy, Polysomnography & Questionnaires

The volunteers may be asked to wear a wrist actigraph to measure movement. This watch would be worn for 24 hours per day for 7-14 days. The volunteer may also be asked to fill out questionnaires regarding their sleep patterns. Note: Other methods of assessing sleep patterns may also be used including a portable polysomnogram or a standard, overnight sleep study.

7-14 days

Primary

Evaluation of skin (both in terms of skin aging and skin disease)

The volunteers may have their skin evaluated for skin aging using the SCINEXA tool. Volunteers with psoriasis may have their skin evaluated via PASI and/or PGA assessments. Volunteers may have photographs taken to compare clinical appearance with laboratory and research findings.

Only once during the study or at specific time points depending on what other procedures are being performed

Secondary

Sample Analysis (from skin, blood, urine, saliva and hair follicle samples)

Skin, blood, urine, saliva and hair follicle samples may be collected from some volunteers to look at various markers related to sleep, the circadian rhythm and skin disease.

Only once during the study or at specific time points depending on what other procedures are being performed

Secondary

Skin Barrier Recovery (via TEWL measurement)

Skin barrier recovery via Transepidermal Water Loss (TEWL) measurement may be assessed in some volunteers.

Only once during the study or at specific time points depending on what other procedures are being performed

Secondary

MED Testing & Recovery from UV-induced erythema

MED Testing & Recovery from UV-induced erythema may be assessed in some volunteers.

24 hours

Study Criteria

Inclusion Criteria:

  -  Males or females ages 18 years and above

  -  Capable of giving informed consent

  -  Adults who are either healthy, normal volunteers or those with a skin disease
     including but not limited to eczema, psoriasis, acne or other inflammatory dermatoses

  -  Fitzpatrick Skin Type I-VI

  -  In good general health

  -  Willing to cooperate with study instructions

Exclusion Criteria:

  -  Volunteers 18 years or younger

  -  Any serious medical or physical condition that would cause the subject significant
     discomfort with study procedures

  -  Women who are pregnant, nursing, or who may become pregnant in the next 3 months