Have you or your loved ones been diagnosed with anemia?
You may be eligible to participate in a anemia clinical trial.
Have you or your loved ones been diagnosed with anemia? You may be eligible to participate in a anemia clinical trial.
What is a clinical trial? Is participating in a clinical trial right for you? Learn more
Anemia Clinical Trial
Have you or your loved ones been diagnosed with anemia?
You may be eligible to participate in a anemia clinical trial.
Have you or your loved ones been diagnosed with anemia? You may be eligible to participate in a anemia clinical trial.
Completed
Male & Female
All ages
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors and transfusion related patient outcomes are investigated.
Details for the study
Population
Patients undergoing major elective surgery in General surgery Orthopedics Urology Transplantation surgery Neurosurgery Gynecology and obstetrics Cardiovascular surgery
Brief Title
Investigation of the Transfusion Practices in Surgical Patients in Turkey
Official Title
Investigation of the Transfusion Practices in Surgical Patients in Turkey
Brief Summary
The aim of this study is to describe the transfusion practices in patients undergoing major<br /> surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP)<br /> and platelets; the transfusion predictors and transfusion related patient outcomes are<br /> investigated.
Detailed Description
Patient Blood Management (PBM) is an evidence based multidisciplinary approach for the care
of patients who may need blood transfusion. The aim of PBM is achieving better patient
outcomes by focusing on the patients' own blood as a source.
To date PBM is considered "good transfusion practice" and is being implemented in a growing
number of countries. The Turkish Society of Anesthesiologists PBM Task Force is working on
this subject since 4 years and decided to conduct a study. Before starting a PBM program, the
transfusion practices of clinicians working at diverse surgical fields; differences between
current transfusion practices and PBM strategies; the areas for improvement and the obstacles
that could prevent change could be identified with this study. Data collection will also
serve to identify the current situation as a reference and to control the achievement of the
PBM's aim: improving clinical outcomes. These data will be refered as The Turkish National
Perioperative Transfusion Study (TULIP TS) data.
The aim of this study is to describe the transfusion practices in patients undergoing major
surgery in Turkey.
The study evaluates i. The perioperative transfusion rates of RBCs, FFP and platelets. ii.
With which reasons the anesthesiologists decide to transfuse a patient (co morbidities of the
patients, physiologic transfusion triggers, hemoglobin trigger, uncontrolled bleeding, on
request from surgeon etc.).
iii. The relation of transfusion and the patients co-morbidity index, the P POSSUM score and
SORT score; anesthesia methods; monitorisation methods (hemodynamic, coagulation); amount of
bleeding; type of surgery; type of hospital.
iv. The relation of transfusion and patient outcomes (unanticipated ICU admission, prolonged
ICU stay, acute renal failure, thromboembolic events, ischemic events, pulmonary
complications, cardiac advers events, infections, acute respiratory distress, infection,
all-cause mortality).
Treatments and/or Procedures
Blood transfusion
Transfusion of blood products in the perioperative period in patients undergoing major surgery
Outcome Measures
Outcome measures are the tests that investigators perform to prove whether or not a treatment being tested in a clinical trial is having any effect.
Primary
Postoperative amount of blood products transfused
Postoperative amount of blood products: RBCs,FFP and platelets transfused
Primary
Intraoperative amount of blood products transfused
Intraoperative amount of blood products: RBC's,FFP and platelets transfused
Primary
Preoperative amount of blood products transfused
Preoperative amount of blood products: RBCs,FFP and platelets transfused
Secondary
Mortality
Whether the patient died: all cause mortality
Secondary
Acute respiratory distress
Whether the patient had acute respiratory distress
Secondary
Preoperative anemia
Whether the patient had anemia (Hemoglobin male < 13 female < 12 g/dL)
Secondary
Infection
Whether the patient had infection: wound, pneumonia, urinary, sepsis etc.
Secondary
Ischemic event
Whether the patient had an ischemic event concerning heart, nervous system,limb, gastrointestinal tract etc.
Secondary
Thromboembolic event
Whether the patient had a thromboembolic event concerning lungs (pulmonary embolism), brain (stroke), gastrointestinal tract, kidneys, or extremities etc.
Secondary
Acute renal failure
Whether the patient had acute renal failure
Secondary
Prolonged length of stay in ICU
Whether the patient had a prolonged length of stay in ICU
Secondary
Postoperative transfusion indications
The reasons to decide to transfuse (factors determining transfusion) blood products
Secondary
Intraoperative transfusion indications
The reasons to decide to transfuse (factors determining transfusion) blood products
Secondary
Preoperative transfusion indications
The reasons to decide to transfuse (factors determining transfusion) blood products
Secondary
Unanticipated ICU admission
Whether the patient had an unanticipated ICU admission
Secondary
Preoperative coagulopathy
Whether the patient had coagulopathy due to disease or drugs
Secondary
Pretransfusion hemoglobin values
The hemoglobin concentration before transfusion
Secondary
Pretransfusion hemoglobin values
The hemoglobin concentration before transfusion
Secondary
Advers cardiac events
Whether the patient had an advers cardiac event: myocardial infaction; non fatal cardiac arest; arrhytmia; cardiogenic pulmonary edema etc
Secondary
Pretransfusion hemoglobin values
The hemoglobin concentration before transfusion
Study Criteria
Inclusion Criteria: Patients undergoing major elective surgery Exclusion Criteria: Trauma patients, emergency surgery