Have you or your loved ones been diagnosed with angina pectoris?
You may be eligible to participate in a angina pectoris clinical trial.
Have you or your loved ones been diagnosed with angina pectoris? You may be eligible to participate in a angina pectoris clinical trial.
What is a clinical trial? Is participating in a clinical trial right for you? Learn more
Have you or your loved ones been diagnosed with angina pectoris?
You may be eligible to participate in a angina pectoris clinical trial.
Have you or your loved ones been diagnosed with angina pectoris? You may be eligible to participate in a angina pectoris clinical trial.
Recruiting
Male & Female
18 Years +
The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
Details for the study
Population
The study population includes any patient undergoing isolated coronary artery bypass surgery.
Brief Title
Outcome After Coronary Artery Bypass Grafting
Official Title
E-CABG: European Multicenter Study on the Outcome After Coronary Artery Bypass Grafting
Brief Summary
The E-CABG registry is a multicenter, European registry collecting data on the preoperative<br /> characteristics, treatment strategies and outcome of patients undergoing isolated coronary<br /> artery bypass grafting (CABG).
Detailed Description
Improvements in the surgical treatment of coronary artery disease are possible only when
implementation of current methods and development of new methods are based on the solid
ground of large and reliable clinical data. Furthermore, clinical findings assume even more
significance when detected in study populations from different institutions with
heterogeneous referral pathways, baseline clinical characteristics and perioperative
treatment strategies. The rationale of this European multicenter study is therefore to
prospectively collect data on baseline characteristics, operative and anesthesiological
methods and postoperative outcome of patients undergoing CABG in eleven cardiac surgery
centers from five European countries. This multicenter prospective registrywill provide data
to evaluate the prognostic impact of a number of patients' risk factors as well as the
efficacy and safety of operative methods and drugs used during the pre-, peri- and
postoperative period.
Treatments and/or Procedures
Coronary artery bypass surgery
Patients will undergo coronary artery bypass grafting
Outcome Measures
Outcome measures are the tests that investigators perform to prove whether or not a treatment being tested in a clinical trial is having any effect.
Primary
Mortality
Any death occurring after surgery
Secondary
Nadir hematocrit
Lowest hematocrit level during the operation day
Secondary
Intra-aortic balloon pump
Use of intra-aortic balloon pump for acute heart failure after surgery
Secondary
ECMO
Use of extracorporeal membrane oxygenation for acute heart failure after surgery
Secondary
Repeat revascularization
Any repeat myocardial revascularization procedure performed after surgery
Secondary
Wound infection
Any deep sternal or lower limb wound infection occurring after surgery
Secondary
Blood losses
Amont of blood losses from drainages 12 hours after surgery
Secondary
Use of blood products
Use of any blood product (red blood cell, fresh frozen plasma, Octaplas, platelets) during the in-hospital stay
Secondary
Myocardial infarction
Myocardial infarction (diagnosed by ECG and troponin monitoring) any time after surgery
Secondary
Resternotomy for bleeding
Re-exploration for excessive bleeding
Secondary
Atrial fibrillation
New episode of atrial fibrillation requiring or not cardioversion during the in-hospital stay
Secondary
Renal replacement therapy
Any renal replacement therapy during the in-hospital stay
Secondary
Highest level of serum creatinine
Highest level of serum creatinine during the in-hospital stay
Secondary
Length of stay in the intensive care unit
Length of stay in the intensive care unit after surgery
Secondary
Pericardial effusion
Pericardial effusion requiring medical or surgical treatment
Secondary
Gastrointestinal complications
Any gastrointestinal complication requiring medical or surgical treatment after surgery
Secondary
Use of prothrombotic drugs
Perioperative use of cryoprecipitate, PCC and/or rFVIIa for excessive bleeding PCCs Perioperative use of rFVIIa, PCC, cryoprecipitate
Secondary
Postoperative use of antibiotics
Postoperative use of antibiotics for postoperative infection
Secondary
Prolonged use of inotropes
Use of inotropes > 12 hours after surgery
Secondary
Stroke
Any ischemic brain injury occurring after surgery and lasting > 24 hours
Study Criteria
Inclusion Criteria:
- Patients of aged > 18 years undergoing isolated CABG for stable coronary artery
disease or acute coronary syndrome. Patients undergoing Maze procedure will be
included in this registry.
Exclusion Criteria:
- Patients undergoing any other major cardiac surgery procedure will be excluded from
this registry.