What is a clinical trial? Is participating in a clinical trial right for you? Learn more
Have you or your loved ones been diagnosed with hemophilia a?
You may be eligible to participate in a hemophilia a clinical trial.
Have you or your loved ones been diagnosed with hemophilia a? You may be eligible to participate in a hemophilia a clinical trial.
Completed
Male
All ages
This multicenter, open-label, phase 3 extension study will investigate the safety and efficacy of rVIII‑SingleChain for prophylaxis and on‑demand treatment of bleeding episodes in 50 previously untreated patients (PUPs) with no previous exposure to any FVIII product who achieve at least 50 EDs to rVIII-SingleChain in this study. A substudy (open to both PTPs and PUPs) will investigate the use of rVIII-SingleChain in surgery. A substudy (open to PUPs who develop an inhibitor to rVIII-SingleChain) will investigate the use of rVIII-SingleChain in immune tolerance induction (ITI) therapy.