Are you healthy and looking to help advance medical science?

You may be eligible to participate in a interstitial cystitis clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a interstitial cystitis clinical study, and could be compensated for your time.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Interstitial Cystitis Clinical Trial

NCT01985880 | Observational patient registry

Are you healthy and looking to help advance medical science?

You may be eligible to participate in a interstitial cystitis clinical study, and could be compensated for your time.

Are you healthy and looking to help advance medical science? You may be eligible to participate in a interstitial cystitis clinical study, and could be compensated for your time.

Completed

Male & Female

20 Years +

This study has recruited 67 Participants

The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome

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Details for the study

Population

patients >20 years old with interstitial cystitis control

Brief Title

The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome

Official Title

Experimental Study of Biomarker in Patient With Interstitial Cystitis/Painful Bladder

Brief Summary

The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial<br /> cystitis/painful bladder syndrome

Detailed Description

This is a observational study

Outcome Measures

Outcome measures are the tests that investigators perform to prove whether or not a treatment being tested in a clinical trial is having any effect.

Primary

To compare of expression of the biomarker such as APF, HB-EGF, MCP-1 among the Hunner's ulcer interstitial cystitis and non-ulcer interstitial cystitis and control groups

1month

Secondary

To compare of changes voiding parameters after bladder biopsy between Hunner' ulcer group and non-ulcer group

1 month

Secondary

TO compare of change of scores of questionnaires such as O'Leary-Sant Interstitial Cystitis questionnaire (IC-Q), Pelvic Pain and Urgency/Frequency Patient Symptom Scale(PUF), Visual Analogue Scale (Pain) between Hunner's ulcer group and non-ulcer group

1month

Study Criteria

Inclusion Criteria:

  -  1) must have experienced bladder pain, urinary urgency and urinary frequency, for at
     least 6 months prior to entry into the study 2) Pain VAS ≥4 3) O'Leary-Sant
     Interstitial Cystitis questionnaire (IC-Q) symptom and problem ≥ 12( and pain ≥2, and
     nocturia ≥ 2) 4) PUF score ≥ 13 5) cystoscopic record within 2 years

Exclusion Criteria:

  1. Patients who are pregnancy or, childbearing age without no contraception

  2. Patients with voided volume <40 or, > 400ml

  3. Patients with microscopic hematuria, (≥1+ in dipstick), If not excluded that no
     evidence of neoplastic tumor examination

  4. Patients with urine culture showing evidence of urinary tract infection 1month prior
     to the study

  5. Accompanied medical problem below

       -  Tuberculosis in urinary system

       -  Bladder cancer, urethral cancer, prostate cancer

       -  Recurrent cystitis

       -  anatomical disorder

  6. Patients had prior surgery (eq, bladder augmentation, cystectomy

  7. Patients with neurologic disorder

  8. Patients with indwelling catheter or intermittent self-catheterization

  9. Patients with psychologic problem