Have you or your loved ones been diagnosed with chronic obstructive pulmonary disease (copd)?

You may be eligible to participate in a chronic obstructive pulmonary disease (copd) clinical trial.

Have you or your loved ones been diagnosed with chronic obstructive pulmonary disease (copd)? You may be eligible to participate in a chronic obstructive pulmonary disease (copd) clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial in Edmonton Alberta
NCT01949727 | Observational

Have you or your loved ones been diagnosed with chronic obstructive pulmonary disease (copd)?

You may be eligible to participate in a chronic obstructive pulmonary disease (copd) clinical trial.

Have you or your loved ones been diagnosed with chronic obstructive pulmonary disease (copd)? You may be eligible to participate in a chronic obstructive pulmonary disease (copd) clinical trial.

Completed

Male & Female

50 Years +

This study has recruited 111 Participants

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease primarily caused by smoking. COPD creates a tremendous burden to the healthcare system, as disease exacerbations result in frequent, prolonged hospitalizations. While originally considered a disease specific to the lung, data have shown that COPD is associated with substantial cardiovascular (CV) morbidity and mortality. Exacerbations of COPD requiring hospitalization result in marked patient deterioration, and heightened CV risk. The cause of the increased CV risk with stable COPD, and the exaggerated CV risk during exacerbations of the disease are unknown; however, it may be due to chronic inflammation which is exacerbated with a flare-up of the disease, and/or chronic inactivity which is similarly worsened with bed-rest during a hospitalization. Despite the impact of COPD on healthcare, there are relatively few studies examining how COPD inpatient care impacts on patient outcomes, inflammation and CV risk. Disease management programs, such as pulmonary rehabilitation and patient self-management education, are part of guideline therapy for COPD; however, these are not regularly implemented following a hospitalization, and how these interventions affect patient outcomes, behavior, physical activity, inflammation and CV risk have not been well studied. The proposed long-term project will examine how typical inpatient COPD care, and how early referral to chronic disease management programs after hospital discharge, affect patient outcomes. This grant brings together an outstanding group of researchers who have the necessary clinical, content and methodological expertise to successfully complete this work. These studies will provide invaluable information about inpatient and outpatient management for a disease which has a tremendous impact on healthcare.