Have you or your loved ones been diagnosed with cystic fibrosis?

You may be eligible to participate in a cystic fibrosis clinical trial.

Have you or your loved ones been diagnosed with cystic fibrosis? You may be eligible to participate in a cystic fibrosis clinical trial.

What is a clinical trial? Is participating in a clinical trial right for you? Learn more

Cystic Fibrosis Clinical Trial in Angers
NCT00476281 | Interventional

Have you or your loved ones been diagnosed with cystic fibrosis?

You may be eligible to participate in a cystic fibrosis clinical trial.

Have you or your loved ones been diagnosed with cystic fibrosis? You may be eligible to participate in a cystic fibrosis clinical trial.

Completed

Male & Female

10 Years +

This study has recruited 114 Participants

Diabetes is a important complication of cystic fibrosis (CF). The improved life expectancy of patients with cystic fibrosis, as a result of advances in medical therapy, has resulted in an increasing prevalence of cystic fibrosis-related diabetes (CFRD). CFRD is associated with accelerated pulmonary decline and increased mortality. Pulmonary effects are seen some years before the diagnosis of CFRD implying that impaired glucose tolerance may be very early detrimental. Insulin treatment is clearly indicated in patients with CFRD to control symptoms and reduce complications. However, at the state of impaired glucose tolerance or fasting hyperglycaemia, current screening methods are not suitable for the early management of hyperglycaemia.The recent introduction of the continuous glucose monitoring system (CGMS), which provides a continuous glucose profile, has revealed to be clinically relevant in the investigation of glucose excursions over a long period. This device, widely use in diabetic non cystic fibrosis patients, has been validated in non diabetic cystic fibrosis subjects. Previous studies of continuous glucose monitoring have been realized in CF patients with normal glucose tolerance and diabetes and compared with non CF controlThe aim of our study is to evaluate the glucose profile with continuous glucose monitoring the nutritional and respiratory status in cystic fibrosis subjects, according to their glucose tolerance.