The aim of this study is to identify potential risk factors for fragility fractures in men.

Brief Title

Study of Male Osteoporosis and Aging

Official Title

Study on Male Osteoporosis and Aging

Brief Summary

The aim of this study is to identify potential risk factors for fragility fractures in men.

Detailed Description

Osteoporosis is a disease characterized by decreased bone mass and pathological changes in
the microarchitecture of the bones. The clinical significance of osteoporosis is the
association with fragility fractures and, consequently, increases in both morbidity and
mortality.

In men, genetical and life-style factors are known to affect the risk of fractures, however,
data relating these factors with measures of bone mineral density and fracture risk are
limited.

30.000 men aged 60-70 were randomly selected from the Central Office of Civil Registration in
Denmark. Each receive a questionnaire addressing demographics, potential risk factors of
osteoporosis, past medical history and medication by mail. In case of consent, the
participants will complete a full medical examination including DXA and sampling of DNA if
they have a fragility fracture. At the same time, 2 participants from the study population
will be selected as control. The study period is 10 years.