Adrenal Gland Neoplasms Trials
Adrenal Neoplasm Clinical Trial
Background: - Endocrine neoplasms (tumors) are among the fastest growing tumors in incidence in the United States. Furthermore, it is often difficult to distinguish between benign or malignant tumors in cancers of the thyroid, parathyroid, adrenal gland, and pa...
Recruiting
Male & Female
4 Years +
Adrenal Tumour With Mild Hypercortisolism Clini...
Incidental findings of adrenal tumours,"incidentalomas", occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushing's syndrome, they have an increase...
Recruiting
Male & Female
18 Years +
Cushing Syndrome Clinical Trial
Objective: To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma. Methods: 234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two groups(e.g adrenalectomy group and...
Recruiting
Male & Female
20 - 70
Years old
Adrenal Gland Neoplasms Clinical Trial
Adrenal masses are highly prevalent and detected with high frequency by conventional imaging. Conventional imaging often fails to rule out a malignant lesion. Accordingly, most hormonally inactive adrenal masses removed by surgery are benign adenomas for which surgical removal is ...
Recruiting
Male & Female
30 Years +
Adrenal Incidentaloma Clinical Trial
Standard diagnostic work-up for adrenal incidentalomas (AI) consists of periodical biochemical analysis and CT-scanning in case the initial work-up does not demonstrate the presence of hormonal hypersecretion or adrenocortical carcinoma (ACC), respectively. The overall aim of...
Recruiting
Male & Female
18 Years +
Adrenal Incidentalomas Clinical Trial
The general objective is to evaluate the consequences of surgical removal of SCSI on hypertension and cardiovascular risk factors in order to determine on an evidence-based basis if surgical excision of SCSI is preferable to an intensive medical regimen in patients with hyperten...
Recruiting
Male & Female
18 - 80
Years old
Adrenal Gland Metastases Clinical Trial
The study is designed to to assess the efficacy of ablative SBRT delivered with VMAT technique in oligometastatic patients affected by adrenal gland metastases.
Recruiting
Male & Female
18 Years +
Adrenal Cancer Clinical Trial
In mitotane treated patients, serum cortisol cannot be used to diagnose hypoadrenalism, since mitotane increases cortisol binding globulin levels (CBG), artificially raising total cortisol. Salivary free cortisol (SC) is not affected by CBG alterations, and reflects the free ser...
Recruiting
Male & Female
18 - 80
Years old
Adrenal Gland Neoplasm Clinical Trial
Background: The adrenal gland makes the hormone aldosterone. This helps regulate blood pressure. An adrenal gland tumor that makes too much aldosterone can cause high blood pressure and low potassium. The cause of these tumors is unknown, but sometimes they are inherited. ...
Recruiting
Male & Female
7 - 70
Years old
Cancer, All Types Clinical Trial
The PIONEER Initiative stands for Precision Insights On N-of-1 Ex vivo Effectiveness Research. The PIONEER Initiative is designed to provide access to functional precision medicine to any cancer patient with any tumor at any medical facility. Tumor tissue is saved at time of ...
Recruiting
Male & Female
1 Month - 99 Years
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